Lethal concentration of methyl methanesulfonate in a new potential invertebrate model for ecotoxicology

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Methyl Methanesulfonate

Bacillus subtilis was not inactivated and was able to replicate even though approximately 3 X 104 methyl groups added by methyl methanesulfonate (MMS) were bound to the deoxyribonucleic acid (DNA) of each organism. No significant loss of methyl groups from the DNA occurred for several generations upon incubation of methylated wild-type or MMS-sensitive cells. Single-strand breaks were not obser...

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ژورنال

عنوان ژورنال: Nauplius

سال: 2018

ISSN: 2358-2936

DOI: 10.1590/2358-2936e2018022